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Manisha parthasarathy
Looking for a jobProject Technical Support
Molecular pharmacology researcher at ICMR–NIRT advancing Nanopore targeted sequencing for tuberculosis drug-resistance diagnostics.
IndiaProject Technical Support at III
About
At ICMR–NIRT, I contribute to tuberculosis diagnostics research using targeted next-generation sequencing with Nanopore MinION. I support sequencing, quality control, validation, and analysis for a 26-gene drug-resistance panel for Mycobacterium tuberculosis.
During my PhD at Vellore Institute of Technology, I investigated Andrographis paniculata’s protective effects against methotrexate-induced toxicity in Wistar rats. This work contributed to five first-author publications.
My research spans preclinical pharmacology and infectious disease diagnostics. I’ve worked with molecular biology workflows, BSL-3 sample processing, and preclinical assays, and have contributed to peer-reviewed publications, book chapters, and a pending patent.
At Vellore Institute of Technology, I designed and delivered laboratory practicals and supervised student research projects. I’m seeking an international postdoctoral or industrial research position in molecular diagnostics, infectious disease, or pharmacological research.
Experience
Project Technical Support - III
Executed molecular biology workflows including DNA/RNA extraction, PCR, gel electrophoresis, and library preparation for targeted NGS. Conducted clinical sample processing under BSL-3 biosafety protocols and supported Nanopore MinION sequencing runs for national TB diagnostics research.
DNA RNA ExtractionPCRGel ElectrophoresisLibrary PreparationTargeted SequencingOxford NanoporeBSL 3Quality ControlData AnalysisInventory Management
PhD Researcher
Designed and executed preclinical in vivo studies using Wistar albino rat models, performing biochemical assays, ELISA, Western blot, immunohistochemistry, and histopathological analyses. Published 5 first-author papers in peer-reviewed international journals and presented at international conferences.
Preclinical Research
Education
Vellore Institute of Technology
Doctor of Philosophy in Biosciences & Technology. Dissertation on Andrographis paniculata ameliorating methotrexate-induced toxicities in Wistar albino rats.
Vellore Institute of Technology
M.Sc. in Biotechnology from a 5-Year Integrated Programme with a CGPA of 8.85/10. Dissertation on the protective effect of Madhuca longifolia against diclofenac-induced toxicity.